The federal provisions contain requirements for parental authorization (consent) and consent of children. For research that poses more than a minimal risk and offers no prospect of direct benefit to the child, IRBs may authorize research involving a State Department in certain circumstances. This is the case where the proposed study (1) is related to the status of a common child or (2) in institutions such as schools or hospitals where the majority of children linked to the child are not centres. If such a search is authorized, each child must have an independent and competent designated lawyer (in addition to any other designated guardian). If a minor is detained by the state, the provisions of Part C of the DHHS Regulation that govern the research of prisoners may also be de-incarcerated. A single application and consent process can be all that is required for many studies, such as a single meeting or a short hospitalization and routine follow-up. Further studies should include regular verification of parents` and children`s consent to the child`s participation in research. This can happen every year or more, depending on the nature of the research and perhaps changes in the child`s health. For example, when children come to tests every 6 months, especially for research that does not have the prospect of using them directly, it is usually appropriate to check that they wish to continue to participate. (Some children will report that they are not prepared to continue by convincing their parents not to bring them for testing.) If research evolves in a way that could influence the risk assessment for parents and children in terms of potential benefits, approval and approval should be re-obtained.
When children are asked to do something by parents, doctors, teachers or other adult authorities, they often feel implicit pressure to consent. Similar problems related to social or peer pressure (for example. B for studies in educational institutions) may also arise when recruiting children to participate in research. Caldwell and colleagues (2003) examined 33 Australian parents whose health ranged from health to serious illness. Investigators indicated that parents of sick children, some of whom were or participated in clinical trials, saw the greatest potential for direct or personal benefits from the study. Unsurprisingly, these parents also knew more thieves about school.